This course will provide the most updated information of new drug development in some research fields and human diseases, and to cultivate students who would like to devote themselves to academic institutes or pharmaceutical industry in the future. We provide brief but fundamental knowledge in the pathogenesis of human diseases, and identify novel therapeutic targets which are actively explored by pharmaceutical industry to develop potential therapeutic agents either in the pre-clinical stage or under clinical trials. The pharmacology, toxicology and unmet medical needs of these drugs would be discussed. We would also provide TFDA Regulations and Guidance for Investigational New Drug (IND) and New Drug Application (NDA).